SharePoint 2010 Error: System.Web.HttpException: Directory 'C:\inetpub\wwwroot\wss\VirtualDirectories\80\_catalogs\masterpage' does not exist.

I had got the error when I tried to use pagemethods in SharePoint. I had registered the AjaxControlToolkit namespace in masterpage and then I replace ScriptManager with AjaxControlToolkit’s ToolkitScriptManager as shown below:

<ajaxToolkit:ToolkitScriptManager id="ScriptManager" runat="server" 
EnablePageMethods="true" EnablePartialRendering="true"
EnableScriptGlobalization="false" EnableScriptLocalization="true"/>



The problem was I enabled the pagemethods by setting EnablePageMethos to true. Disabling the pagemethods fixed the issue. However I didn’t explore why there’s the error if pagemethods is enabled.



So disable the pagemethods by setting EnablePageMethods=”false” and then then error will disappear…

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